SCIENCE CHINA Materials•2026•DOI: 10.1007/s40843-025-3503-9
This correction addresses an image misuse in the original publication (Sci China Mater, 2025, 68(6): 2095, DOI: 10.1007/s40843-025-3311-6). Specifically, a fluorescent image in Fig. 4d, depicting live/dead cells after treatment with MPDA@TMZ without laser irradiation, was erroneously presented. The corrected Fig. 4 is provided, and the authors confirm that the results and conclusions of the original paper remain unaffected. The correction ensures the integrity of the reported data, particularly the cell viability and apoptosis assays. The study focuses on mesoporous bowl-shaped polydopamine (MPDA) nanoparticles co-loaded with temozolomide (TMZ) and indocyanine green (ICG) for synergistic glioblastoma therapy. The corrected figure includes CLSM images of G422 cells after incubation with various formulations (ICG, sPDA@ICG, mPDA@ICG, MPDA@ICG), cell viability curves, quantitative fluorescence intensity, live/dead staining, and apoptosis quantification. Statistical significance is denoted as ****p < 0.01. The correction maintains the scientific validity of the findings, which demonstrate the potential of MPDA-based nanoplatforms for combined chemo-photothermal therapy.
Environmental Chemistry•2026•DOI: 10.7524/j.issn.0254-6108.2025022302
The escalating environmental contamination by mercury ions (Hg2+) poses severe risks to ecosystems and human health, necessitating the development of rapid, sensitive, and cost-effective detection methods. In this study, Fe1-xS@CNT composite nanozymes were synthesized via a straightforward solvothermal approach. The nanozymes exhibit uniform morphology, structural stability, and significant peroxidase (POD)-like activity. The incorporation of carbon nanotubes (CNT) facilitates electron transfer, enhancing the Fenton reaction between Fe2+/Fe3+ to generate abundant reactive oxygen species (ROS), primarily hydroxyl radicals (·OH) and superoxide anions (·O2−). The synergistic action of these ROS and photogenerated holes (h+) promotes the oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) to a blue-colored product (oxTMB), establishing a colorimetric system of Fe1-xS@CNT + H2O2 + TMB. The specific binding of S2− on the nanozyme surface to Hg2+ inhibits POD activity, reducing the absorbance of the system. This principle was harnessed to develop a colorimetric method for Hg2+ quantification in environmental water samples. The method demonstrates a linear range of 0.1–500 μg·L−1 and a limit of detection (LOD) of 0.04 μg·L−1. Validation in real water samples (campus and tap water) showed recoveries between 94.4% and 111.1% with relative standard deviations (RSD) below 3.0%, comparable to atomic fluorescence spectrometry. The method offers advantages of simplicity, rapid analysis, and naked-eye visibility, providing a novel approach for on-site monitoring of heavy metal pollutants.
SCIENCE CHINA Materials•2025•DOI: 10.1007/s40843-025-3311-6
Glioblastoma (GBM) remains a lethal malignancy with a five-year survival rate of 6%, and standard temozolomide (TMZ) chemotherapy is constrained by short plasma half-life and insufficient tumor accumulation. This study reports a mesoporous polydopamine nanocarrier with a bowl-like morphology co-loaded with indocyanine green (ICG) and TMZ (MPDA@ICG/TMZ) for combined photothermal therapy (PTT) and chemotherapy. The nanoplatform exhibits a photothermal conversion efficiency of 43.88% under 808 nm laser irradiation. The bowl-shaped morphology significantly enhances cellular uptake relative to conventional mesoporous nanospheres. Hyperthermia amplifies TMZ cytotoxicity, reducing cell survival to 17.2% in vitro. In GBM-bearing nude Balb/C mice, MPDA@ICG/TMZ accumulates in tumors via the enhanced permeability and retention (EPR) effect, visualized by second near-infrared window (1000–1700 nm) fluorescence imaging. The combined treatment achieves complete tumor cell eradication in vitro and in vivo under 808 nm laser illumination. These results establish MPDA@ICG/TMZ as a potent nanoplatform for synergistic chemotherapy and PTT, offering a promising direction for GBM treatment.
SCIENCE CHINA Materials•2025•DOI: 10.1007/s40843-025-3560-5
Perovskite oxides have been recognized since 2014 as oxygen anion intercalation pseudocapacitive electrodes, a mechanism fundamentally distinct from bulk-diffusion-controlled battery redox. Pseudocapacitance in these materials arises from surface Faradaic reactions involving OH− adsorption, oxygen vacancy-mediated anion migration, and reversible transition metal valence changes (e.g., Mn2+→Mn3+→Mn4+ in LaMnO3±δ). The primary bottleneck is low energy density, compounded by a narrow voltage window (<0.5 V) due to water decomposition in 6 M KOH. This perspective examines the interplay of electronic structure—localized density of states near the Fermi level and spin-electron states—with OH− adsorption/desorption, oxygen ion mobility, conductivity, oxygen vacancy concentration, and interface reconfiguration. Hydroxyl metal oxide formation during cycling facilitates interface reconstruction, boosting capacity without foreign additives. Alternative electrolytes (organic, ionic liquid, Water-in-Salt) are proposed to widen the voltage window. The assembly of perovskite electrodes with suitable anodes into high-performance devices remains the ultimate goal. Key challenges persist in electrolyte selection, interface stability, and scalable manufacturing, necessitating deeper mechanistic understanding beyond empirical electrochemical performance.