• • The PTD/PCC sIPN achieves a maximum shear strength of 150.5 kPa under physiological conditions, outperforming conventional biological glues and providing robust tissue adhesion critical for withstanding intravascular pressure.
• • The device exhibits autonomous self-deployment at 37 °C, enabling on-demand shape recovery triggered by body temperature, which simplifies deployment procedures and reduces the risk of migration.
• • In vitro hemocompatibility is exceptional with hemolysis below 3%, and cell migration is enhanced by up to 38.9%, indicating excellent biocompatibility for vascular applications.
• • In vivo, the material promotes angiogenesis with CD31 expression increased by 162.18% and αSMA by 154.93% compared to control, demonstrating its potential to accelerate vascular healing.