Chinese Journal of Environmental Engineering•2026•DOI: 10.12030/j.cjee.202507030
Arsenic is a toxic metalloid predominantly present in water as As(V) and As(III), whose speciation governs toxicity and mobility. Conventional speciation methods (HPLC-ICP-MS, IC-HG-AFS) offer ultralow detection limits but suffer from high cost, long analysis times, and non-portability, hindering on-site rapid monitoring. This study presents a sulfide-based spectrophotometric method exploiting the quantitative reaction between As(V) and S2− to form monothioarsenate (H3AsO3S) with a characteristic absorption at 233 nm. Under optimized conditions (H+ concentration 1 mol·L−1, Na2S dosage 5 mmol·L−1, reaction time 3 min, N2 purging 2 min), As(V) is directly quantified. Total arsenic is determined after complete oxidation of As(III) to As(V) using NaClO (10 mmol·L−1, pH 12, 5 min), and As(III) is obtained by difference. The method exhibits linearity over 0.5–50 mg·L−1 (A = 0.0209c + 0.0627, R² = 0.999), a detection limit of 0.17 mg·L−1, spike recoveries of 101.9%–104.1%, and relative standard deviation of 1.06%. Validation against real industrial wastewater samples showed relative deviations <10% compared with HPLC-ICP-MS and IC-HG-AFS. Total analysis time is within 15 min. The method is simple, cost-effective, and suitable for field monitoring.
SCIENCE CHINA Materials•2026•DOI: 10.1007/s40843-025-4010-4
Liver fibrosis, a critical pathological consequence of chronic liver injury, remains a therapeutic challenge due to its complex mechanisms and limited effectiveness of conventional treatments. Recent advancements in two-dimensional (2D) nanomaterials, such as graphene derivatives, transition metal dichalcogenides (TMDs), black phosphorus nanosheets (BPNSs), MXenes, and layered double hydroxides (LDHs), have created novel opportunities for antifibrotic therapy. These materials exhibit exceptional physicochemical properties, including ultrahigh surface area, tunable surface chemistry, biocompatibility, and photothermal/electrochemical functionalities, enabling multifaceted interventions in fibrosis progression. The core therapeutic strategies mainly involve modulating hepatic stellate cells (HSCs) activation, inhibiting excessive extracellular matrix (ECM) deposition, and alleviating oxidative stress and inflammatory responses. However, 2D nanomaterials still face great challenges, such as long-term biosafety, precise functionalization for tissue-specific targeting, and scalable synthetic methods. This review systematically summarizes the recent breakthroughs in anti-fibrosis strategies based on 2D nanomaterials, elucidates their potential mechanisms of action, and explores the prospects for clinical translation of these nanoplatforms. Serving as a nexus between materials science and hepatology, 2D nanomaterials offer revolutionary prospects for precision medicine applications in hepatic fibrosis management.