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Verified CAS / Academic Author2 Decoded Studies

Prof. Bingran Yu

Beijing University of Chemical Technology

Co-Affiliations:Key Laboratory of Biomedical Materials and Engineering, Beijing University of Chemical Technology

Research Publications & English Decoded Briefs

Showing 2 publications
SCIENCE CHINA Materials2026DOI: 10.1007/s40843-026-3961-8

Correction to: Flexible electrostatic hydrogels from marine organism for nitric oxide-enhanced photodynamic therapy against multidrug-resistant bacterial infection

This correction addresses an inadvertent misplacement of Fig. 4b3 during figure reorganization in the original article published in Science China Materials, volume 65, issue 10, 2022, page 2850 (DOI: 10.1007/s40843-022-2024-6). The corrected Fig. 4b is presented herein. The authors confirm that this correction does not affect the results, conclusions, text, or figure caption of the original work. The correction was requested by the authors and received on 6 January 2026, accepted on 8 January 2026, and published online on 10 February 2026. The original study introduced flexible electrostatic hydrogels derived from marine organisms for nitric oxide-enhanced photodynamic therapy against multidrug-resistant bacterial infections. The correction ensures the accurate representation of experimental data, maintaining the integrity of the scientific record.

SCIENCE CHINA Materials2026DOI: 10.1007/s40843-026-4150-2

Injectable Hydrogel with Photothermal Antibacterial Properties for Accelerating Infected Wound Healing

Bacterial infection and irregular wound morphology are major challenges in clinical wound management. Injectable hydrogels can conform to irregular wound geometries but often lack antimicrobial activity. Here, we report an injectable hydrogel (HPAu gel) formed by sequentially mixing phenylboronic acid-modified hyaluronic acid (HA-PBA) and chloroauric acid under alkaline conditions. The gel's internal multiple crosslinks enable uniform encapsulation of in situ-generated gold nanoparticles. Hydrogen bonds and phenylboronic acid ester bonds confer self-healing, injectability, and adhesion, allowing effective sealing of irregular cavities. In vitro, the hydrogel exhibits long-lasting photothermal stability and eliminates multiple bacterial strains. In a mouse dorsal full-thickness infected wound model, HPAu gel under near-infrared (NIR) irradiation eradicated Staphylococcus aureus, reduced inflammation (TNF-α fluorescence area significantly lower; IL-10 area 12.88‰ vs <2‰ in Blank), promoted vascular regeneration (CD31 and α-SMA expression increased), and accelerated wound healing. This work presents a promising strategy for treating irregular infected wounds.