• • Achieves 99.999% (5-log) inactivation of E. coli within 40 minutes under visible light, with photocatalytic efficacy retained over five consecutive reuse cycles, indicating robust operational stability critical for clinical and environmental deployment.
• • The redox-mediated stabilization strategy maintains Au25 nanocluster size and structural integrity under ambient storage and light irradiation, directly addressing aggregation-induced deactivation that typically reduces catalytic activity by orders of magnitude.
• • Type-II heterojunction formation between Au25 NCs and UiO-66-NH2 enhances visible-light harvesting and charge separation efficiency, enabling efficient O2 activation to ROS; this translates to a 40-minute disinfection timeframe, outperforming many conventional photocatalytic systems that require hours.
• • Integration into wearable fabrics demonstrates continuous antibacterial protection, with the composite retaining high efficacy after five reuse cycles, underscoring potential for low-maintenance, durable antimicrobial textiles in healthcare and hygiene-critical environments.