reCAPTCHA Bot Shield Active Verifying human reader & generating high-resolution document...
Verifying Document Integrity15s remaining
Protected by Google reCAPTCHA v3.•Privacy•Terms Key Findings in This Report
• • Metal ions act as dynamic signaling molecules via non-covalent interactions, enabling rapid immune modulation; this contrasts with stable covalent modifications, offering reversible control for therapeutic intervention.
• • Metal-based nanomaterials, such as Fe-Ce6 nanoparticles, achieve bacterial microenvironment-responsive nanozyme generation and photodynamic antibacterial activity, accelerating infected wound healing (Sci China Mater, 2025, 68: 2962–2972).
• • Copper ionophores combined with autophagy interference amplify cuproptotic stress and antitumor immunity, as demonstrated in J Control Release (2025, 388: 114262), highlighting a dual-mechanism strategy.
• • Magnesium-based nanoflowers in controlled-release hydrogels synergize immunomodulation and cartilage regeneration in tendon-bone healing (Bioactive Mater, 2024, 36: 62–82), indicating metal-ion delivery systems can address tissue repair bottlenecks.