Interlocking integration of elastic strain sensor yarn enables smart and distributed sensing in healthcare clothing

• • The double-covered elastic strain sensor yarn achieves a stretchability of 170% and a gauge factor of 414, enabling high-sensitivity detection of physiological movements while maintaining mechanical robustness under repeated deformation. • • The sensor-clothing interlocking structure is breathable, washable, and abrasion-resistant, ensuring durability for daily wear and repeated laundering, which is essential for clinical adoption in long-term health monitoring. • • A wearable respiratory monitoring belt for COPD assessment produced sensing data comparable to commercial portable devices, demonstrating clinical validity and potential for replacing bulky spirometry in home settings. • • Smart clothing with distributed sensing monitored Parkinson's disease motor symptoms with 96.67% accuracy using deep learning algorithms, highlighting the system's capability for objective, continuous assessment of neurodegenerative disorders.