• • Achieved a photocatalytic Minisci-type cross-coupling rate of 40 mmol g_cat−1 h−1 under LED irradiation and 10.9 mmol g_cat−1 h−1 under natural sunlight, representing a significant improvement over conventional photocatalysts that require 5–48 h for 0.2 mmol-scale reactions, thus enabling faster synthesis for pharmaceutical intermediates.
• • The ultra-thin g-C3N4 nanosheets possess a high specific surface area of 120 m2 g−1, which enhances substrate adsorption and accelerates surface electron transfer, directly boosting photocatalytic efficiency and enabling gram-scale synthesis, a critical step toward industrial scalability.
• • The catalyst exhibits excellent recycling stability, as demonstrated by successful reuse without significant loss of activity, reducing catalyst cost and waste in continuous manufacturing processes.
• • The protocol operates under mild conditions using LED or natural sunlight, eliminating the need for stoichiometric oxidants and Ag catalysts used in classical Minisci reactions, thereby reducing environmental impact and operational hazards.