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Dual-mode electrotunable near-infrared chiral organic synaptic photodiodes for intelligent cancer detection

Authors: Liuting Shan; Yongjie Cai; Lixuan Liu; Weilong Huang; Xiaolong Li; Shuai Liu; Yang Yang; Zhixiang Wei; Jingchang Sun; Huipeng Chen

DOI: 10.1007/s40843-025-3786-8Status: Verified Translated Edition
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Key Findings in This Report

• • The device achieves a photocurrent dissymmetry factor (g_ph) dynamically tunable up to -0.06 under positive bias, enabling hardware-level synaptic weight adjustment for enhanced image contrast. • • Under negative bias, the device operates as a highly sensitive CPL detector, enabling efficient chiroptical signal acquisition and imaging for cancer cell samples. • • In OCNN-based cancer detection, CPL detection accuracy reaches 83%, approaching the theoretical 87% and outperforming natural light detection at 65%. • • The dual-mode operation (negative bias for detection, positive bias for synaptic processing) integrates sensing and computation in a single hardware platform, reducing signal transmission losses and improving processing efficiency.