• • The review covers recent advances in aromatic foldamers and supramolecular helical assemblies, with a focus on chiral phenomena during helical secondary structure formation, as evidenced by references to studies on chirality transfer and amplification (e.g., Nagata et al., ACS Cent Sci 2019, 5:1235–1240).
• • Absolute control of helical handedness in quinoline oligoamides has been achieved using chiral moieties such as β-pinene-derived pyridyl groups and oxazolylaniline, as demonstrated by Kendhale et al. (J Org Chem 2011, 76:195–200) and Zheng et al. (Org Lett 2017, 19:1482–1485).
• • Strong chiral amplification in copolymers of biphenylylacetylenes has been reported, with unexpected enhancement/inversion and memory of macromolecular helicity (Ishidate et al., J Am Chem Soc 2019, 141:7605–7614).
• • Supramolecular 'sergeants' strategy enables in situ and multi-level induction of chirality in helical assemblies of triarylamine trisamide monomers, as shown by Perennes et al. (Chem Sci 2025, 16:14584–14594).