• • The catalyst enantiomer purity regulation strategy enables precise control over regioselectivity in ring-opening polymerization, yielding chiral poly(2-hydroxybutyric-co-glycolic acid) with G–G linkage contents varying from X% to Y% (exact values not provided in the text, but the strategy allows tunability).
• • Thermo-mechanical properties, including glass transition temperature (Tg) and tensile modulus, are directly correlated with polymer microstructure; adjusting catalyst enantiomer purity allows modulation of Tg over a range of Z°C (exact values not specified).
• • This approach circumvents the need for synthesizing multiple ligand variants, offering a more efficient route to tune polymer properties compared to traditional ligand regulation strategies.
• • The synthesized chiral polymers exhibit tunable properties that are essential for biomedical applications, where degradation rates and mechanical performance must be matched to specific clinical requirements.