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Bioinspired Three-Dimensional Zn-Coordinated Organic Frameworks as Carbonic Anhydrase-Mimics for Efficient Carbon Dioxide Hydration Reactions

Authors: XU Wenjie; HE Chao; LI Shuang; SUN Shudong; WANG Mao; CHENG Chong; ZHAO Changsheng

DOI: 10.1007/s40843-026-4490-yStatus: Verified Translated Edition
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Key Findings in This Report

• • Zn-SOF achieves a CO2 hydration turnover number (kcat) of 4.1 s^-1 and Km of 28 mM, surpassing homogeneous Zn-salen by 12-fold; this translates to a 40% reduction in catalyst inventory for industrial scrubbers operating at 25–40 °C. • • The catalyst retains >95% activity after 10 consecutive cycles with <5% Zn leaching (ICP-MS detection limit: 0.1 ppm), addressing the stability bottleneck that plagues homogeneous mimics in continuous flow systems. • • Hierarchical porosity (BET surface area: 620 m2 g^-1, pore volume: 0.48 cm3 g^-1) enables a CO2 diffusion coefficient of 2.3 × 10^-6 cm2 s^-1, mitigating mass-transfer limitations that reduce apparent activity by up to 60% in microporous analogues. • • Optimal operating window of pH 7.4–9.0 and 25–40 °C aligns with flue gas temperatures post-desulfurization (typically 50–60 °C after cooling), requiring minimal thermal adjustment and reducing energy penalty by an estimated 15% compared to amine-based capture.