Atomic-Level Chelation Engineered Ni-Salicylate MOFs with Hierarchical Nanobelt Assemblies for Selective Glucose Electrooxidation

• • Ni-SA-2 exhibits a sensitivity of 5.97 mA mM−1 cm−2 and a detection limit of 0.71 μM (S/N = 3), enabling trace-level glucose quantification in clinical diagnostics and food quality control. • • The catalyst retains 85.4% of its initial current after 8 h continuous operation, indicating robust operational stability critical for long-term implantable or industrial sensors. • • The synthesis is extended to isostructural M-SA analogs (M = Co, Fe, Cr, Mn) under identical conditions, demonstrating a universal platform for tunable electrocatalyst design. • • The hierarchical nanobelt architecture maximizes active site accessibility and facilitates mass transport, directly improving reaction kinetics and sensor response time.