A Sulfobetaine Polyurethane for Substitutable Meniscus Implant with Excellent Mechanical, Tribological, and Biological Properties

• • PU-CL-hSB meniscus implant withstands a maximum force of 26.08 N, surpassing native meniscus (25.14 N), indicating superior load-bearing capacity for clinical substitution. • • Energy dissipation over 300 cycles ranges from 45.93 to 39.17 N mm for PU-CL-hSB versus 28.83 to 19.11 N mm for native meniscus, demonstrating enhanced shock absorption and fatigue resistance. • • Friction coefficient of PU-CL-hSB (0.08–0.19) is lower than native meniscus (0.11–0.26), ensuring superior lubrication and reduced wear on articular cartilage. • • In vivo rabbit study over 8 and 25 weeks confirms no inflammatory response and protection of articular cartilage, validating biocompatibility and functional stability for long-term implantation.