• • Tunable mesopore sizes from 9.1 to 40.0 nm and particle diameters from 45.5 to 1020 nm enable precise matching to guest molecules ranging from enzymes to catalyst nanoparticles, directly impacting separation and catalysis performance.
• • Single-crystalline meso-MOFs with well-defined lattice fringes along [010], [110], and [111] directions and FFT patterns showing co-existing microscopic and mesoscopic order (slight deviation from p6mm) ensure structural integrity and low defect density, critical for mechanical and thermal stability under industrial operating conditions.
• • The HCl/CH3COOH acid pair decouples crystallization (CH3COOH-controlled) from micelle co-assembly (HCl-controlled), eliminating the formation of amorphous nanoparticles or non-mesostructured nanocrystals that occur with single-acid systems, thereby providing a robust kinetic window for scalable synthesis.
• • Demonstrated architectures (hexagonal, columnar, dendritic, worm-like) and morphologies (cube, octahedron, 2D intersecting nanosheets) with multivariate ligands and metal ions confirm general feasibility, reducing the need for specialized equipment and multi-step post-synthetic treatments that plague hard-templating routes.