A Self-Powered Electrical Stimulation Suture for Muscle Tissue Repair in Rabbits

• • The SES-suture accelerated wound healing by a factor of 1.6 compared to commercial sutures in a rabbit muscle incision model, demonstrating a significant improvement in postoperative recovery rate. • • Immunofluorescence analysis revealed that α-SMA and CD31 expression in the SES group was approximately 2.8 and 3.2 times higher than the blank group, respectively, indicating enhanced muscle fiber formation and angiogenesis. • • The suture is composed entirely of absorbable materials (magnesium, polylactic acid, polycaprolactone), ensuring biodegradability and eliminating the need for suture removal, which reduces patient discomfort and infection risk. • • The rabbit model was selected due to its closer approximation to human musculoskeletal physiology compared to rodents, providing more clinically relevant data for translational research.